Semaglutide and GLP-1 Overview

GLP-1 short for glucagon-like peptide-1 is a short, naturally occurring peptide hormone just 30-31 amino acids in length. Its primary physiologic function is to lower blood sugar levels by naturally enhancing insulin secretion. It also plays a role in protecting beta cell insulin stores by promoting insulin gene transcription and has been linked with neurotrophic effects in the brain and central nervous system. In the GI system, GLP-1 has been shown to significantly decrease appetite by delaying gastric emptying and reducing intestinal motility.  Preliminary research has shown impacts of GLP-1 in the heart, fat,  muscles, bones, liver, lungs, and kidneys as well.